Methods: Case note examination and literature review of nasal amyloidosis was undertaken using Pubmed and the Cochrane database.
Results: A patient presented with unilateral nasal obstruction and was found to have left sided nasal polyposis. Immunohistochemistry assisted the diagnosis of non-AA amyloid from the nasal biopsies. Investigations for systemic amyloidosis were negative.
Conclusion: This is the first documented case in the literature of localised nasal amyloid of non-AA subtype. Due to the rare presentation of this pathology there is limited data regarding optimal management to prevent recurrence.